Definitely should be okay from GOG. Getting old games to function on new systems is pretty much the entire rationale for their existence.
Sales page definitely indicates that it should work:
Works on: Windows (XP, Vista, 7, 8, 10)
And nothing in the recent user comments to indicate otherwise.
As Wlad mentioned earlier, both are available on GOG Sale at the moment:
https://www.gog.com/game/vampire_the_masquerade_bloodlines @ $4.99
https://www.gog.com/game/vampire_the_masquerade_redemption @ $1.49
(You can add both to your cart simultaneously from either sales page. Scroll down to the section headed Buy Series and click the “BUY ALL SERIES FOR $6.48” link.)